23 Jul Preparation method and application of angiogenesis model
Abstract
The invention provides a preparation method and application of an angiogenesis model. The method includes the following steps that firstly, vascular endothelial cells are inoculated to matrigel to primarily form vasoganglion; secondly, type I collagen is added to stimulate secondary angiogenesis. The preparation method is suitable for simulating the pathogenesis process of angiogenesis in joint synovial tissue and particularly suitable for simulating and building angiogenesis conditions in temporo-mandibular joint synovial tissue of a human body, and provides a new platform for research of action modes of new cytokines in the aspect of angiogenesis promotion or inhibition. The model is simple in manufacturing material and short in consumed time and has good development, expansion and tissue engineering application prospects.
Year: 2016
Country: CN
Doc No: 105802903