23 Jul Preparation and usage of fibroin albumen antipriming pipe
Abstract
The preparation and the purpose of a silk fibroin protein porous duct relates to the biological material field, in particular to the tissue engineering scaffold field. The invention is to arrange silk fibroin aqueous solution with 30 percent to 50 percent of high concentration in a vessel, the solution is formed into silk fibroin fiber with the diameter of 200 nm to 3000 nm under the function of electrostatic force with 500 V to 60 kV voltage, the fiber is received by a revolving metal rod or tube, the receiving distance is in 5 to 100 cm, and after 5-480 minutes, the silk fibroin porous duct with the diameter of 1 to 10 mm, the wall thickness of 0.01 to 1 mm and the length not lower than 30 cm can be obtained. Then the silk fibroin porous duct is processed with 90 to 10 percent of methyl alcohol aqueous solution to lead the silk fibroin porous duct to be denaturized, after the vacuum drying in the normal temperature, the non water-soluble silk fibroin protein porous duct is obtained. The diameter of the silk fibroin duct of the invention is controllable, the invention has the biological compatibility and the porosity which are beneficial to the cells to grow, and can be used as a tissue engineering scaffold, the preparation process is easy and feasible, the cost is low, and the commercialization production can be realized.
Year: 2008
Country: CN
Doc No: 101156967