23 Jul Porous material for tissue engineering stent
Abstract
The invention discloses a porous material for a tissue engineering stent. The porous material for the tissue engineering stent is prepared from 25-40% of polycaprolactone, 30-45% of polyethylene oxide and 25-40% of sodium bicarbonate according to a method as follows: uniformly mixing the raw materials; extruding in a twin-screw extruder for granulating; foaming and moulding by a conventional microporous foaming and moulding technology to obtain an intermediate product; leaching the obtained intermediate product in a circulating water bath; and performing vacuum drying to obtain a porous material with the porosity of 68-74.0%, the pore size of 20-200 microns, and the sizes of internal intercommunicating passages of about 20-200 microns. The porous material for the tissue engineering stent has the advantages as follows: in the foaming process, not only supercritical carbon dioxide for microporous foaming and moulding can generate a foaming action, but also gas obtained by decomposing sodium bicarbonate can generate a foaming action, so that by a combined physical and chemical foaming method, the finally obtained porous material can meet a growth requirement of a biological cell.
Year: 2014
Country: CN
Doc No: 103520770