23 Jul POROUS HYDROXYAPATITE CERAMICS WITH BIMODAL DISTRIBUTION OF PORES AND METHOD FOR MANUFACTURING THEREOF
Abstract
The proposed porous hydroxyapatite ceramics with a bimodal pore distribution and preparation method thereof belongs to field of medicine, traumatic and orthopedics, usable in maxillofacial surgery as scaffolds for tissue engineering or drug delivery systems, as well as fillers in bone (spongy parts) defects. Hydroxyapatite powder is used as basic material, glycerol as plasticizer, de-ionized water as moistening agent, and ammonium bicarbonate as a pore-former substance. Ceramic manufacturing technology is based on the foaming process in situ.The new technical quality of invention is working out ceramics with a bimodal pore distribution and preparation method thereof that provides total porosity of 65 to 75 % containing 53 to 62 % open macro-porosity with pore’s diameter in the range from 50 to 500 micro-meters, and micro-porosity with pore’s diameter in range from 0.05 to 0.2 micro-meters. Closed porosity is 12 to 14 %. Compressive strength of ceramics is 8 to 11 MPa.Composition of ceramic mass and its fabrication method provides implant biocompatibility, porosity with interconnected pore system (macro- and micro-pores), that stimulates the body’s cell growth and increases the adsorption of proteins and mechanical properties that corresponds to quality of trabecular bone.
Year: 2012
Country: LV
Doc No: 14492