23 Jul Porous composite scaffold for bone tissue engineering and preparation method therefor
Abstract
The invention relates to a biological field and specifically to a porous composite scaffold for bone tissue engineering and a preparation method therefor. The porous composite scaffold for bone tissue engineering provided by the invention is a hydroxyapatite/nanocrystal cellulose/silk fibroin porous scaffold; the porous composite scaffold is a three-dimensional porous composite scaffold prepared from hydroxyapatite, nanocrystal cellulose and silk fibroin; and the porosity is 90-95% and the aperture is 180-220[mu]m. According to the hydroxyapatite/nanocrystal cellulose/silk fibroin porous scaffold, hydroxyapatite and nanocrystal cellulose are uniformly distributed in the scaffold, so that the scaffold is excellent in mechanical performance; in addition, the scaffold is high in biocompatibility and capable of supporting and promoting osteogenic differentiation of mesenchymal stem cells; and meanwhile, the preparation method is simple in process, wide in raw material sources, high in production efficiency, low in cost, and can be applied to industrial large-scale production.
Year: 2016
Country: CN
Doc No: 105521525