23 Jul Polymer with anti-cancer property and preparation method and application of polymer
Abstract
The invention discloses a polymer with an anti-cancer property and a preparation method and application of the polymer, and belongs to the field of biomedical engineering materials. Hyperbranched polyamidoamine which contains disulfide bonds is obtained by Michael reaction; and growth of tumor tissue cells is inhibited by inherent pharmacological activity of the hyperbranched polyamidoamine, but the hyperbranched polyamidoamine does not have side effects on normal tissue cells. The preparation method is gentle, and is convenient to operate, by-products are less, products are easy to separate and purify, and biological compatibility of the material is facilitated. The polymer with the anti-cancer property is simple in material component, has easily obtained raw materials and is good in biological compatibility, has obvious curative effect when independently used as a potential anti-tumor drug, and does not need to be loaded with drugs additionally; and a large number of modifiable functional groups on the surface of the polymer support application of the polymer in preparation of the biomedical engineering materials, and the polymer with the anti-cancer property is expected to be widely applied to the field of biomedical engineering materials.
Year: 2018
Country: CN
Doc No: 108530646