23 Jul Polylactic acid-hydroxyapatite whisker compound porous scaffold for bone tissue engineering and preparation method thereof
Abstract
The invention relates to a polylactic acid-hydroxyapatite whisker compound porous scaffold for bone tissue engineering and a preparation method thereof, and belongs to the field of biomedical material technique application. The compound porous scaffold is prepared from, by weight, 0.5%-50% of hydroxyapatite whiskers and 50%-99.5% of polylactic acid. The compound porous scaffold is prepared by adopting a solvent casting-vacuum volatilizing-particle leaching method, the technology is simple, operation is convenient, and the yield is stable; according to the prepared compound porous scaffold, the porosity is 45.8%-91.1%, the diameter of irregular straight-through holes is 50-600 micrometers, the compressive strength is 1.2-19.1 MPa, the cell toxicity is qualified, and the good clinical application prospect is achieved.
Year: 2016
Country: CN
Doc No: 105797215