23 Jul Polyaniline-base injectable photo-thermal hydrogel
Abstract
The invention discloses polyaniline-base injectable photo-thermal hydrogel which is binary-system hydrogel composed of alpha-cyclodextrin and a water-soluble high-polymer photo-thermal material. The water-soluble high-polymer photo-thermal material is polyethylene glycol grafted poly-N-phenylglycine comprising a main chain and a side chain, and the main chain is poly-N-phenylglycine (PPG) while the side chain is polyethylene glycol (PEG). The hydrogel has good photothermal conversion capability and can be used for photothermal therapy, meanwhile, the hydrogel can load chemotherapy drugs, photodynamic reagents and fluorescence imaging reagents to respectively obtain a photo-thermal hydrogel carry system which has chemotherapy, photodynamic therapy and imaging functions and is a biocompatible multifunctional photo-thermal response-type carrier hydrogel system, and the hydrogel has broad application prospect in drug carriers, photocontrol drug release, photothermal therapy, photodynamic therapy, tissue engineering and the like.
Year: 2016
Country: CN
Doc No: 105457026