Piston-shaped tissue engineering bone and application thereof

Piston-shaped tissue engineering bone and application thereof

Abstract

The invention relates to a piston-shaped tissue engineering bone and application thereof. The piston-shaped tissue engineering bone is prepared by the following steps: 1, culturing and inducing bone seed cells; 2, preparing a piston-shaped bone repair scaffold; and 3, combining the bone seed cells and the bone repair bracket in vitro and culturing, wherein the bone seed cells cultured to a second generation are combined with the bone repair scaffold in the step 3 to form a compound of the bone seed cells and the bone repair scaffold. Similar to the tissue structures and characteristics of a normal orbital wall, the orbital wall tissue engineering bone constructed and cultured in vitro can facilitate autogenous bone regeneration while a scaffold material is degraded, generate reasonable bone reconstruction and finally be replaced by autogenous bone tissues in vivo so as to realize dual-repair of the shape and the function. The piston-shaped tissue engineering bone is applied in the field of the defect repair of the orbital walls and cranial bones.

Year:  2010

Country:  CN

Doc No:  101628128

 

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