23 Jul PEG hydrogel and preparation method thereof as well as tissue engineering scaffold prepared by PEG hydrogel
Abstract
The invention relates to a PEG hydrogel. The PEG hydrogel comprises a crosslinking structure, the crosslinking structure is obtained by covalent combination and crosslinking of 4-arm-PEG-MAL and matrix metalloprotease substrate peptide through maleimide group on 4-arm-PEG-MAL and SH- group on the matrix metalloprotease substrate peptide. The invention also relates to a preparation method of the PEG hydrogel, an application of the PEG hydrogel in preparation of a tissue engineering scaffold, and the prepared tissue engineering scaffold. The PEG hydrogel is prepared in a low-concentration triethanolamine buffer, gluing time is fast, and under prerequisite that the physical and chemical properties are basically guaranteed, the damage or loss of carried seed cells and a drug is reduced as possible.
Year: 2017
Country: CN
Doc No: 106519632