23 Jul Pancreatic cancer drug tolerance detection method and kit
Abstract
The invention belongs to the field of genetic engineering, and particularly relates to a pancreatic cancer drug tolerance detection method and kit. Expression of miR-584, miR-153, miR-188 and miR-483 in a pancreatic cancer drug-tolerant tissue sample is remarkably higher than that of the same in a pancreatic cancer normal tissue sample, which can serve as a pancreatic cancer drug-tolerance screening marker to provide accurate clinical medication guidance for clinical patients. The pancreatic cancer drug tolerance miRNA detection kit takes combined use of miR-584, miR-153, miR-188 and miR-483 as a pancreatic cancer drug tolerance detection index and is based on fluorescent real-time quantitative PCR (polymerase chain reaction); the kit is quick and convenient in detection, high in detection sensitivity and specificity, low in cost, capable of meeting needs on detecting tolerance of most of pancreatic cancer drugs, extremely wide in application range and high in prediction accuracy through clinical verification.
Year: 2017
Country: CN
Doc No: 107034283