Oxidized alginate/polyacrylamide interpenetrating network based medical composite homogeneous-phase stent and preparation method thereof

Oxidized alginate/polyacrylamide interpenetrating network based medical composite homogeneous-phase stent and preparation method thereof

Abstract

The invention belongs to the technical field of medical tissue engineering, relates to a medical stent, and particularly relates to an oxidized alginate/polyacrylamide interpenetrating network based medical composite homogeneous-phase stent and a preparation method thereof. Natural alginate is taken as a main research object, and by compounding of bioactive substances such as polyacrylamide, hydroxyapatite and gelatin, defects of poor mechanical properties, difficulty in degradation in a human body, lack of cell special binding sites and the like in application of the alginate to tissue engineering are overcome by means of combination of an interpenetrating network, homogeneous-phase crosslinking, partial oxidation, surface modification and bioactive growth fact controlled release.

Year:  2019

Country:  CN

Doc No:  110305253

 

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