23 Jul Novel freeze-drying platelet-rich fibrin, as well as preparation and application thereof
Abstract
The invention discloses a preparation method of a novel freeze-drying platelet-rich fibrin. The method comprises steps of: centrifuging the fresh blood to obtain the gel-like platelet-rich fibrin (PRF), freeze drying the gel-like platelet-rich fibrin for 24 hours in the vacuum low-temperature environment of 400 Pa and minus 45-minus 4 DEG C so as to obtain the freeze-drying platelet-rich fibrin (PRF) with bioactivity, and preparing the sheet, granular or powdery freeze-drying platelet-rich fibrin (PRF) according requirements so as to be used for preparing trauma auxiliary materials, tissue engineering scaffolds or other biological materials for recombination use. The method can maintain the activity of the fresh PRF, so that the PRF can be easily and refrigerated for a long time, is convenient and flexible to use, can be used as the trauma auxiliary material or the scaffold material to be compounded with other tissue engineering materials and can be applied to war injury repair and tissue defect repair.
Year: 2013
Country: CN
Doc No: 103272258