23 Jul Non-homogeneous hydrogel and preparation method and application thereof
Abstract
The invention discloses non-homogeneous hydrogel and a preparation method and an application thereof, and belongs to the field of biomedical materials. The non-homogeneous hydrogel comprises gelatinized continuous phases and gel microspheres which are distributed in the continuous phases. The preparation method comprises the following steps: firstly dispersing a water solution of a gel material into an oily solution and carrying out emulsification and gelatinization treatment to obtain the gel microspheres; and building the non-homogeneous hydrogel from the gel microspheres and the gel material. The hydrogel is non-homogeneous, and different materials or same materials with different properties can be adopted to load different cells or same cells with different densities, so as to build the hydrogel material in non-homogeneous distribution. The non-homogeneous hydrogel is beneficial to rebuilding of tissues or organs, has a wide application prospect in the field of tissue engineering, and can also be used for building a multi-cell limited contact three-dimensional co-culture system.
Year: 2015
Country: CN
Doc No: 104353123