23 Jul Natural high-molecular acrylate and its preparation method
Abstract
The invention relates to a synthesis method of natural high-molecular acrylate products. The method comprises the steps of: adding a polysaccharide taken from one of chitosan, hyaluronic acid or alpha, beta, gamma-cyclodextrin into a mixed solution of an acid binding agent and chloralkane in a volume ratio of 1-2:1, stirring and placing the mixed solution under room temperature for 48h; cooling and stirring the mixed solution in an ice bath at a temperature of 0-5DEG C for 2h; adding dropwisely a chloralkane solution of 20-40 wt% of unsaturated acyl chloride for 2-4h, controlling the added unsaturated acyl chloride of 2-4 times the weight of the polysaccharide; raising the temperature to 25-30DEG C for a reaction of 8h, and washing the filtered precipitate with acetone for 3 times, thus obtaining a natural biological polysaccharide derivative. The natural biomaterial acrylate product of the method provided in the invention can be used for tissue engineering scaffold materials, drug controlled slow release materials, and UV (ultraviolet)-curing paint materials.
Year: 2012
Country: CN
Doc No: 102391391