23 Jul Nanofiber jointly modified by SAB and heparin and preparation and application thereof
Abstract
The invention relates to a nanofiber jointly modified by SAB and heparin and preparation and application thereof. The fiber comprises a shell layer which comprises SAB-MSN and a high molecular polymer, and a core layer which comprises the heparin. The method comprises the steps of preparation of SAB-MSN, preparation of a shell layer spinning solution, preparation of a core layer solution and preparation of the nanofiber. The method is simple and efficient, and the price is low. The core layer and the shell layer of the nanofiber carry drugs simultaneously, and the double sustained release effect can be achieved; the good biocompatibility and blood compatibility are achieved, and the nanofiber has excellent application prospects in vascular tissue engineering.
Year: 2019
Country: CN
Doc No: 110409014