MULTILAYERED SILK SCAFFOLDS FOR MENISCUS TISSUE ENGINEERING

MULTILAYERED SILK SCAFFOLDS FOR MENISCUS TISSUE ENGINEERING

Abstract

Provided herein is a biocompatible implant for meniscus tissue engineering. Particularly, the biocompatible implant comprises a multi-layered crescent-shaped silk fibroin scaffold, in which each layer comprises distinct pore size and/or pore orientation, e.g., to mimic native meniscus complex architecture. Accordingly, the biocompatible implant can be used for repairing any meniscal defect or promoting meniscal regeneration in a subject.

Year:  2011

Country:  WO

Doc No:  2011156586

 

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