23 Jul Multi-arm star polyester/hyperbranched polyglycidyl ether and preparation method thereof
Abstract
The invention discloses multi-arm star polyester/hyperbranched polyglycidyl ether which comprises biodegradable polyester and polyglycidyl ether, the composed molecular shape takes the shape of a star which comprises a core, a support arm and a hyperbranched part, wherein the core is a residual part after compounds containing at least three hydroxyls are reacted, the support arm is biodegradable polyester, the hyperbranched part is polyglycidyl ether and has a structural general formula as below, wherein R is hyperbranched polyglycidyl ether. The invention also discloses a preparation method of the multi-arm star polyester/hyperbranched polyglycidyl ether. The multi-arm star polyester/hyperbranched polyglycidyl ether not only has biodegradability, but also can satisfy the requirements of control release of different drugs, medical product materials and tissue engineering as the structure simultaneously contains a hydrophobic part and the hydrophilic hyperbranched part, especially a great deal of terminal hydroxyls reserved in the structure can also be bonded with other drugs and various ligands to form a multifunctional medicine carrier.
Year: 2010
Country: CN
Doc No: 101717499