23 Jul Mineralized bone tissue engineering scaffold and preparation method thereof
Abstract
The invention discloses a mineralized bone tissue engineering scaffold. The mineralized bone tissue engineering scaffold comprises a porous polyester/amphiprotic ionized hydrogel composite scaffold and a calcium-phosphate mineralization material formed in the porous polyester/amphiprotic ionized hydrogel composite scaffold in situ, wherein the porous polyester/amphiprotic ionized hydrogel composite scaffold comprises a porous polyester bone scaffold and amphiprotic ionized hydrogel compounded in the porous polyester bone scaffold. The invention also discloses a preparation method of the mineralized bone tissue engineering scaffold. The composite scaffold is capable of carrying out efficient sustained release of bone growth factors, giving efficient bone conduction and bone induction performance to the surface of the overall scaffold, accelerating functional repair of bone defects under ultralow dosage of rhBMP-2 and improving the biological safety performance of the scaffold material.
Year: 2019
Country: CN
Doc No: 109432495