23 Jul Micro/nano-fiber bone repairing scaffold and production method thereof
Abstract
The invention discloses a micro/nano-fiber bone repairing scaffold. The scaffold is obtained by adding composite particles to degradable polymers of engineering scaffolds for bone repair and producing micro/nano-fibers. The composite particles are provided with a core-shell structure, the core is a polymer particle prepared by high polymer materials or a bionic active microsphere similar to a bone structure in a micro-scale, the shell is medical biodegradable inorganic salt, and the bionic active microsphere similar to the bone structure in the micro-scale is composed of high polymer materials and inorganic salt. The micro/nano-fiber bone repairing scaffold has high activity and is capable of better absorbing and inducing cells to grow; the medical biodegradable water insoluble inorganic salt shell can protect collagen, growth factors and/or medicine in the composite particles, and repair of bone tissue is facilitated due to the bionic active microsphere similar to the bone structure in the micro-scale with an inorganic-organic intercalated structure and a human body simulation structure.
Year: 2012
Country: CN
Doc No: 102671244