23 Jul Methods of treating amniotic membranes using supercritical fluids and compositions and apparatuses prepared therefrom
Posted at 13:41h
in methods
Abstract
A method of sterilizing compositions prepared from amniotic membrane tissues may include harvesting placental tissue, separation of amniotic membrane tissue, and treatment of the amniotic membrane tissue with a supercritical fluid such as carbon dioxide. Treatment with supercritical fluid may subject the amniotic membrane tissue to conditions sufficient to sterilize the tissue yet maintain at least some biological function of the sterilized composition. The tissue preparations and compositions having a sterility assurance level of at least 10−6 described herein may be used as tissue grafts, wound dressings, cell culture substrates, or other substrates for use in tissue engineering.
Year: 2015
Country: US
Doc No: 2015367020