23 Jul METHODS OF PRODUCTION OF FIBROUS FIBRINOGEN SCAFFOLDS AND PRODUCTS THEREOF
Abstract
The present invention relates to methods for producing fibrous fibrinogen biomaterials that can be used as three-dimensional scaffolds. The methods of this invention enable the controlled detachment of fibrous fibrinogen scaffolds in vitro. The fibrous fibrinogen biomaterials generated by the methods of this invention can be detached in a solution. Alternatively, the fibrous fibrinogen scaffolds of this invention can be immobilized on a surface. The fibrous fibrinogen biomaterial can be used in medicine, such as in wound healing, regenerative medicine, dermal reconstruction, skin repair, bone vessel repair, blood vessel regeneration, tissue engineering, and implant coatings. The biomaterials can be generated ‘on-demand’ and can be transferred to a site of injury, such as to a wound.
Year: 2019
Country: WO
Doc No: 2019228676