23 Jul Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing scaffold for tissue engineering
Abstract
A method of manufacturing hydrogel microparticles comprising one or more species of living cells attached thereon and/or encapsulated therein is provided. The method includes dissolving a hydrogel-forming agent in an aqueous medium to form a solution; suspending one or more species of living cells in the solution to form a cell suspension; dispersing the cell suspension into an organic oil to form a microemulsion; and subjecting the microemulsion to conditions that allow the hydrogel-forming agent to form hydrogel microparticles comprising one or more species of living cells attached thereon and/or encapsulated therein. Composition comprising a mixture of a degradable hydrogel and at least one hydrogel microparticle having one or more species of living cells, and a method of manufacturing a scaffold for tissue engineering are also provided.
Year: 2015
Country: CN
Doc No: 104582747