23 Jul Method for treating articular cartilage defect and magnetic focusing instrument used in method
Abstract
The invention discloses a method for treating an articular cartilage defect and a magnetically marked cell targeted transplantation controlled magnetic focusing instrument special for the method. The characteristic that superparamagnetic iron oxide (SPIO) marked stem cells have magnetic property is utilized, and the transmission path of the stem cells is controlled under the action of magnetic forces in different directions and SPIO, so that the stem cells are accurately transplanted to a position with a cartilage cell defect, and the aim of treatment is fulfilled; meanwhile, after the special magnetic focusing instrument is adopted, the motion path of the SPIO marked stem cells can be conveniently and accurately controlled by controlling the power-on condition, current size (magnetic force size) and magnetic force direction of each magnetic coil, and interlink among the cells in the vertical direction can be promoted under the action of the magnetic forces and the SPIO, so that a bracket-free three-dimensional stem cell lamellar tissue engineering structure is constructed. The instrument has a simple structure and is convenient to control and easy and convenient to operate.
Year: 2012
Country: CN
Doc No: 102302822