23 Jul Method for stabilizing mesenchymal stem cell sourced cartilage tissue phenotype
Abstract
The invention discloses a novel application of mesenchymal stem cells decorated by CNP genes, and aims at using the mesenchymal stem cells modified by CNP to maintain the phenotype of the cartilage tissue. The mesenchymal stem cells are obtained by infecting the mesenchymal stem cells with recombinant adenoviruses containing the CNP genes, the cell is used for a seed cell of the cartilage tissue engineering, and a purpose of the phenotype of the cartilage tissues formed by differentiation can be achieved. The method has important guiding significance in the application of the cartilage defect restoration of cartilage tissue engineering, a foundation is laid for realizing the clinical restoration of the tissue engineering cartilage, and the application prospect is wide.
Year: 2017
Country: CN
Doc No: 107012120