23 Jul Method for producing hydroxy alkanoic acid polymer
Abstract
The present invention discloses the production process of hydroxy alkanoic acid polymer. The hydroxy alkanoic acid polymer is prepared with Sinorhizobium fredii as production strain, carbohydrate as carbon source and ammonium salt as nitrogen source, and through high density fermentation and metabolism regulation with caprate in optimal culture medium and under optimal culture condition to obtain 3-hydroxy butyric acid-3-hydroxy caprylic acid polymer. Corresponding fermentation management method, separation and purification method and quality detection method are established. The present invention can obtain 3-hydroxy butyric acid-3-hydroxy caprylic acid polymer product up to 10.7-16.4 g/L, of molecular weight of 127000-137000 Da, and endotoxin content 4-6 EU/g, and the novel nanometer level material may be used in biomedicine and medical tissue engineering.
Year: 2005
Country: CN
Doc No: 1648150