23 Jul Method for preparing tissue engineering scaffold by pore forming of directional soluble fibres
Abstract
The invention provides a method for preparing a tissue engineering scaffold, which comprises the steps of: a) preparing sucrose into sucrose fibres; b) dissolving a biodegradable macromolecular polymer into a solvent; c) paving the sucrose fibres in a mould, and adding polymer solution prepared in the step b) into the mould; d) evaporating the solvent from complex solution prepared in the step c) to prepare a polymer and sucrose fibre complex; and e) putting the prepared polymer and sucrose fibre complex into water to separate out the sucrose. The invention also provides the tissue engineering scaffold prepared by using the preparation method. In the method for preparing the tissue engineering scaffold, the sucrose fibres are used as a pore forming agent, and the tissue engineering scaffold prepared by introducing a fibre pore forming method has a fibrous porous structure with directional arrangement and run-through interconnection, and is low in closed porosity and high in porosity.
Year: 2010
Country: CN
Doc No: 101716372