23 Jul Method for preparing tissue engineering frame
Abstract
The embodiment of the invention discloses a method for preparing a tissue engineering frame. The tissue engineering frame is obtained by processing biodegradable polymer fibers in supercritical CO2 and by controlling processing temperature and processing temperature. The supercritical CO2 has certain dissolvent properties and can generate a micro-melting effect on the surfaces of the biodegradable polymer fibers, so when CO2 is discharged by decompression, the molten parts of contacted surfaces of biodegradable polymer fibers are solidified and crosslinked together to form the tissue engineering frame with high mechanical performance. Thus, the preparation method provided by the invention can complete the crosslinking and melting of fibers at a relatively lower temperature without dissolvent, crosslinker and the like, and generates no cytotoxicity.
Year: 2011
Country: CN
Doc No: 102068716