23 Jul Method for preparing spinal cord injury repair tissue engineering stent
Abstract
The invention relates to a method for preparing a spinal cord injury repair tissue engineering stent. The problems that any complicated model cannot be made, a requirement of a spinal cord bracket model cannot be met, and the porosity is low exist in the conventional method. According to the method, an in-vivo biotic environment is used as an important basis for designing a tissue engineering spinal cord stent by adopting a low temperature forming technology and a porogenic agent leaching process; the spinal cord bracket is partitioned into a grey matter induction functional region and a white matter induction functional region by using a microporous isolation layer with a small size by simulating a spinal cord structure and a living environment, so that the tissue engineering spinal cord stent is made; and an aim of respective regeneration is fulfilled by planting different seed cells and growth factors by using two different biotic environments. According to the method, a made mellow and full and regular stent has macroscopical pores with good penetration property, contains a large quantity of irregular microporous structures, has the average porosity of 89.92 percent and better mechanical property, and can meet the requirement of the tissue engineering spinal cord stent.
Year: 2012
Country: CN
Doc No: 102512266