23 Jul Method for preparing polyelectrolyte nano fibers in core-shell structures by parallel electric field inductive phase separation method
Abstract
The invention relates a method for preparing polyelectrolyte nano fibers in core-shell structures by a parallel electric field inductive phase separation method. By taking natural products hyaluronic acid and chitosan oligosaccharide as raw materials, the polyelectrolyte nano fibers in core-shell structures are prepared by adopting a high voltage electrospinning technique by means of preparing soluble polyelectrolyte mixed liquor of the natural products hyaluronic acid and chitosan oligosaccharide. According to the invention, phase separation is carried out on polycationic electrolyte and polyanionic electrolyte induced by a parallel electric field, so that the nano fibers in core-shell structures are successfully prepared. The nano fibers in core-shell structures prepared by the invention has the effects of resisting bacteria and stopping bleeding and inhibiting growth of cancer cells and good water retention characteristic, meaning that the effects of resisting bacteria and stopping bleeding and inhibiting growth of cancer cells of the chitosan oligosaccharide of the shell as well as the good water retention effect of hyaluronic acid of the core layer. The nano fibers have a good application prospect in biological tissue engineering, medicines or genetic vector materials, biomedical materials and the like.
Year: 2014
Country: CN
Doc No: 103789874