23 Jul Method for preparing pH-value-sensitive crosslinked fiber through low-temperature photopolymerization
Abstract
The invention provides a method for preparing pH-value-sensitive crosslinked fiber through low-temperature photopolymerization. The pH-value-sensitive crosslinked fiber provided by the invention is obtained by carrying out low-temperature photopolymerization reaction on a pH-value-sensitive photopolymerization monomer and poly(ethylene oxide) diacrylate under the initiation of a free radical photoinitiator, and can be used as a pH-value-sensitive tissue engineering scaffold, intelligent hydrogel and a drug controlled release carrier. The method comprises the steps of dissolving the pH-value-sensitive photopolymerization monomer, poly(ethylene oxide) diacrylate and the photoinitiator into water; carrying out low-temperature freezing to freeze water to form a crystal; and then, carrying out low-temperature illuminating and crosslinking as well as freeze drying to remove water to obtain the pH-value-sensitive crosslinked fiber. The method has the characteristics of simple preparation process, high speed and capability of finishing material crosslinking and fiber forming processes through one-step reaction.
Year: 2015
Country: CN
Doc No: 104894672