23 Jul Method for preparing nano fiber coating bracket for promoting bone regeneration
Abstract
The invention belongs to the field of tissue engineering, aims to solve the problems that in the prior art a magnesium alloy bracket is rapid in degradation velocity and poor in corrosion resistance,and discloses a method for preparing a nano fiber coating bracket for promoting bone regeneration. The method comprises the following steps: firstly, dissolving Gel and ciprofloxacin (Cip) into an organic solution, preparing a spinning liquid, collecting a Gel-Cip nano fiber layer on the surface of a Ca-Mg alloy by using an electrostatic spinning technique, and further performing cross-linking inglutaraldehyde steam, thereby obtaining a Mg-Ca alloy bracket with a Gel-Cip nano fiber coating. The method provided by the invention is simple, the Mg-Ca alloy bracket with the Gel-Cip nano fiber coating is relatively high in corrosion resistance, biological compatibility and bacterial resistance, and has wide application prospects in nano coating fiber materials for bone regeneration.
Year: 2018
Country: CN
Doc No: 107715176