23 Jul Method for preparing medical knee joint semilunar cartilage
Abstract
The invention relates to a preparation method of a medical knee joint meniscus, the steps mainly include that: silk with the high quality is firstly selected to be crocheted into a silk meniscus which takes a shape of wedge, the outer edge of the silk meniscus is thicker than the inner edge, and the medical knee joint meniscus can be prepared by degumming, drying, silk protein fiber-collagen compound shaping and other steps. The invention has the advantages of convenient production, low cost and so on, when in use, the transplantation operation is simple, convenient, safe and reliable, the tolerance of patients is good and the immunogenicity is small. As the silk protein fiber after the removal of sericin has good mechanical properties and biocompatibility, the invention can bear the functions of knee joint stabilization, load conduction, articular cartilage protection and lubrication of the natural meniscus at the early stage of the transplantation, at the same time, the invention has the function of a tissue engineering scaffold, and can support the cell growth and blood vessel growth at the advanced stage of the transplantation and be gradually degraded and absorbed along with the regeneration of the real natural meniscus, so the invention provides a new choosing path for the treatment of the patients with the seriously damaged and apraxia knee joint meniscus.
Year: 2008
Country: CN
Doc No: 101209356