23 Jul Method for preparing injectable chitosan hydrogen for tissue engineering
Abstract
The invention discloses a method for preparing an injection chitose aqueous gel used in tissue engineering, grafting the methacrylic acid and lactic acid onto the chitose molecular chain in order with carbodiimide condensation method, the got chitose derivative possesses the polymerized carbon-to-carbon unsaturated bond and water solubility. Employing the redox initiating system of ammonium peroxodisulfate and tetramethylethylenediamine to make the chitose derivative form into chitose aqueous gel through double bond cross-linking. The chitose aqueous gel is non toxic, biodegradable and biological compatibility. The process of the invention is simple and can be used for injection aqueous gel cradle in the tissue engineering.
Year: 2006
Country: CN
Doc No: 1799645