23 Jul Method for preparing dicarboxylanilin pentamer cross-linking chitosan polymer
Abstract
The invention provides a soluble electroactive polymer prepared from aniline pentamer crosslinked chitosan with two terminated carboxyl groups, and a preparation method. The invention provides a series of crosslinked polymer containing electroactive aniline pentamer, which are synthesized from aniline pentamer with two terminated carboxyl groups via two synthesis methods, wherein the first synthesis method condensates activated carboxyl group of aniline pentamer with amido of chitosan in the mixture solvent of acetate water solution and organic solvent to obtain product, and the second method condensates protected chitosan and aniline pentamer in organic solvent to obtain product. The crosslinked chitosan has the advantages of aniline pentamer and natural macromolecule, has electric activity and biological activity, which can be dissolved in acid water solution, be degraded biologically, while the degraded product can be discharged externally. The inventive product is mainly used as biological medical material, particularly as tissue engineering scaffold material of nerve and heart.
Year: 2008
Country: CN
Doc No: 101186656