Method for modifying tissue engineering scaffold and application thereof

Method for modifying tissue engineering scaffold and application thereof

Abstract

The invention relates to a method for modifying a tissue engineering scaffold by employing a molecule layer-by-layer assembly technology. The method comprises the following steps of: (a) soaking the tissue engineering scaffold in aqueous solution with active ingredients I for 1-8 hours; (b) taking out the tissue engineering scaffold subjected to the step (a) and cleaning excessive active ingredients I; (c) soaking the tissue engineering scaffold subjected to the step (b) in aqueous solution with active ingredients II for 1-8 hours; (d) taking out the tissue engineering scaffold subjected to the step (c) and cleaning excessive active ingredients II; and (e) repeating the steps (a) to (d) for n times, wherein n is more than or equal to 0 and less than or equal to 100. The invention also provides a tissue structure and application of the tissue engineering scaffold. The method is carried out in a normal temperature water system, the active ingredients are assembled in a tissue engineering scaffold network layer by layer through interaction between the active ingredients and the tissue engineering scaffold, the assembled components and layers are adjustable, and the method is simple, practical, high in controllability and low in cleaning cost.

Year:  2013

Country:  CN

Doc No:  102940909

 

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