23 Jul Method for inducing Muse cells in adult bone marrow into neural precursor cells (NPCs)
Abstract
The invention relates to the technical field of cytobiology, and provides a method for separating Muse cells from adult bone marrow and inducing into Muse-NPCs in vitro and also performs identification on the Muse cells and induced Muse-NPCs in the aspects of morphologic observation, cell phenotype, multiway differentiation capacity, tumorigenesis and the like. The related molecular markers for the Muse cells and Muse-NPCs cultured by the method are completely expressed. The invention also provides the Muse cells separated from adult bone marrow according to the method and the Muse-NPCs obtained by performing induced differentiation on the Muse cells. The Muse-NPCs are successfully induced to form in vitro, and can provide new favorable seed cells for cellular therapy of nerve injury and tissue engineering therapy in future by utilizing the characteristics of continuous proliferation, multiway differentiation and self derivation.
Year: 2015
Country: CN
Doc No: 104946590