23 Jul Method for fixing biological macro molecule pattern on polymer active surface by micro transfer technology
Abstract
The microwave transfer process of fixing biological macromolecule pattern to the active surface of polymer includes selectively ‘mounting’ biological macromolecule to the micro wells of polydimethyl siloxane stamp; forming one condensated water layer on the surface; dissolving biological macromolecule in water of the micro well and of transverse diffused area and producing chemical reaction in solution; and fixing biological macromolecule in pattern on the active surface of the polymer. The process is simple, flexible and repeatable, and the micro pattern has high contrast and fastness. The cheap process of fixing biological macromolecule in pattern is especially suitable for the less reaction activity biological moecule/active surface system. The present invention has excellent application foreground in constructing biological device, tissue engineering, cell biological research, etc. based on cells.
Year: 2003
Country: CN
Doc No: 1425958