23 Jul Method for fixing biological macro molecule in common pattern on inorganic silicone material surface
Abstract
The fixing process of biological macromolecule on inorganic silicon material surface in common pattern includes the following steps: amination and aldehydration treatment of the inorganic silicone material surface; polydimethyl siloxane stamp micro contact printing on the surface to form one biological macromolecule miro pattern; dropping one other biological macromolecule solution to fix in the uncovered area; and washing and ultrasonic treatment to form the co-pattern fixation of two kinds of biological macromolecules. The said process is simple, controllable and repeatable and has imld reaction condition. The present invention has excellent application foreground in selective cell adhesion, direction induction, cell-based biological device making, tissue engineering, etc.
Year: 2003
Country: CN
Doc No: 1425920