23 Jul Method for evenly coating cell adhesion hardening agent from intermediate medium to the stephanoporate framework or the pipe hole wall surface
Abstract
The invention provides a method for coating cell agglutination enhancer on the hole wall surfaces of porous frame or pipeline made of natural or synthetic material. The method comprises the following steps: coating one or more cell agglutination enhancers on a medium surface and molding the medium; casting the natural or synthetic frame material on the molded medium with a coating; removing the medium material and transferring the cell agglutination enhancer uniformly from the medium surface to the hole wall surface of the porous frame. The cell agglutination enhancer is inlaid in the hole wall surface, even embedded inside the frame substrate. The coating structure can increase coating strength between the coating material and the frame. The coating enables the frame to have cell recognition signal, improves seeding, distribution and reproduction of cells, and facilitates formation of new tissue and blood vessel. The method can be applied according to different tissue engineering requirements to carry out coating and modification on surfaces of porous frame or pipeline with respective coating material.
Year: 2008
Country: CN
Doc No: 101116755