23 Jul METHOD FOR CULTURE OF NEURAL CREST STEM CELLS AND USES THEREFOR
Abstract
The present invention relates to a method for culturing peripheral nerve-derived neural crest stem cells; the neural crest stem cells cultured by the method; a differentiation method; and a cell therapeutic agent and a therapeutic agent for treating neurological disorders, containing the neural crest stem cells. The method comprises the steps of: impregnating peripheral nerve tissues into hydrogel and culturing the peripheral nerve tissues; and decomposing the hydrogel and collecting neural crest stem cells transferred and grown in the hydrogel from the peripheral nerve tissues. The neural crest stem cells have in vivo proliferation ability and pluripotency into all cells forming peripheral nervous system and central nervous system, thereby being applied to the production of a novel drug such as a cell therapeutic agent and a tissue engineering therapeutic agent, a cell biological and molecular biological basic study, and a study on novel drug development.
Year: 2013
Country: KR
Doc No: 20130124076