23 Jul Method for creating microvessel networks, endothelial original vessels, tissues, and human coronary artery substitutes
Abstract
The invention provides a method for creating microvessel networks, endothelial original vessels, tissues, and human coronary artery substitutes. The microvessel networks are produced in vitro from tissue-engineered parent vessels (200,202) sprouting into a supporting matrix, as for example gels, of extracellular matrix proteins. The microvessel systems are integrated into devices that allow for controlled perfusion with fluids. The vessels may include cells from one cell type, for example, endothelial cells, or from combinations of two or more cell types. The miniature provided is suitable for multifunctional vessel systems applied to artificial tissues of biological engineering.
Year: 2013
Country: CN
Doc No: 103468634