23 Jul Method for constructing tissue-engineered pulsating tissue
Abstract
The invention relates to the fields of biomedical engineering technology and regenerative medicine and particularly relates to a method for constructing a tissue-engineered pulsating tissue. According to the method disclosed by the invention, stem cells derived from brown adipose are induced into sinuatrial-node-like cells, and the sinuatrial-node-like cells are implanted onto collagen sponge to construct the tissue-engineered sinuatrial-node-like pulsating tissue in vitro. The tissue-engineered tissue with pulsating characteristics obtained by virtue of the method provides a tissue model for a research on screening of arrhythmic drugs and brings hope for treatment of arrhythmic diseases caused by sick sinus syndrome and auriculo-ventricular block.
Year: 2014
Country: CN
Doc No: 104232571