23 Jul Method and application of MicroRNA (micro ribonucleic acid) 221-3p in preparation of epidermal cells
Abstract
The invention relates to the field of biotechnology, in particular to a novel application of MicroRNA (micro ribonucleic acid) 221-3p to promotion of epidermal cell proliferation, and provides an application of MicroRNA 221-3p to preparation of a reagent for promoting epidermal cell proliferation. The reagent comprises but is not limited to MicroRNA 221-3p, a recombinant vector containing a MicroRNA 221-3p coding gene, a recombinant virus containing the MicroRNA 221-3p coding gene, and a recombinant virus vector containing the MicroRNA 221-3p coding gene. The experiment proves that MicroRNA 221-3p can inhibit expression of PTEN (phosphatase and tensin homolog deleted on chromosome ten) and remarkably increase epidermal cell proliferation speed, and the characteristics of epidermal cells are not lost; MicroRNA 221-3p relates to epidermal cell proliferation. The invention provides novel thought and mode for quickly proliferating the epidermal cells and quickly obtaining tissue engineering skin.
Year: 2015
Country: CN
Doc No: 104561101