Macromolecule polymer scaffold material preparation method based on micro-fluidic technology

Macromolecule polymer scaffold material preparation method based on micro-fluidic technology

Abstract

The present invention provides a macromolecule polymer scaffold material preparation method based on a micro-fluidic technology. According to the method, a liquid droplet micro-fluidic device is used to rapidly produce a lot of uniform liquid droplets or spherical particles, and the liquid droplets or particles are adopted as the pore forming agent and are densely dispersed in an organic solvent with a dissolved macromolecule polymer so as to prepare the macromolecule polymer scaffold material with characteristics of specific morphology and uniform pore; the scaffold material prepared through the method has characteristics of uniform product, good repeatability, uniform pore distribution, uniform pore diameter, wide pore size adjustment range, controllable material shape, and the like; with the method, all preparation steps after the material feeding are completed by the one micro-fluidic device, the product collected from the micro-fluidic device terminal is the prepared final product, and the characteristics of full-automated preparation method and the like are provided; and the prepared scaffold material has the micron-scale size, is hopefully further amplified to the millimeter scale size even the centimeter scale size, and is suitable for being applied in micro-part tissue engineering.

Year:  2016

Country:  CN

Doc No:  105617464

 

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