23 Jul Injectable strengthened phosphate lime/hydrogel microcapsule tissue engineering bone as well as preparation method and application thereof
Abstract
The invention discloses an injectable strengthened phosphate lime/hydrogel microcapsule tissue engineering bone which is prepared from the following components in percentage by weight: 20-75% of calcium phosphate cement, 20-75% of chitosan, 1-10% of PLGA electric spin and 3-155 of hUCMSCs hydrogel microcapsule. The invention also discloses a preparation method of the tissue engineering bone and application of the tissue engineering bone as a bone defect repairing material. The tissue engineering bone not only maintains original good biocompatibility and osteogenesis inducing property of phosphate lime, but also obviously improved mechanical properties and capability for carrying seed cells. The tissue engineering bone can be used for treating bone defect or bone deficiency caused by various diseases and has the characteristics of easy operation, convenient molding, maximum wound reduction, operation difficulty reduction, patient pain alleviation, less infection danger, less scar formation and the like.
Year: 2011
Country: CN
Doc No: 101934095