23 Jul HYDROXYAPATITE AND BIOGLASS-BASED PELLETS, PRODUCTION PROCESS AND APPLICATIONS OF THEREOF
Abstract
The present invention refers to hydroxyapatite and bioglass-based pellets of homogeneous size and spherical shape, whose interconnective porous structure, in the micrometer range, allows for an enhanced osteoconductivity and osteointegratioh, with specific application as a synthetic bone graft and to the respective production process. The production process is based on the pharmaceutical technology of extrusion and spheronization employing a porogenic agent and applying a sinterization stage. in the presence of a vitreous liquid phase, which reverts on behalf of a higher reproducibility, superior yield and greater production capacity. Therefore, the present invention is destined to the production of hydroxyapatite and bioglass-based pellets with applications. in osteoregenerative medicine, particularly in the fields of orthopaedic surgery, maxillofacial surgery, dental surgery, implantology and as tissue engineering scaffolds
Year: 2010
Country: WO
Doc No: 2010021559