23 Jul Hyaluronic acid and polyethylene glycol composite fiber membrane material and preparation method and application thereof
Abstract
The invention relates to a biodegradable and bioabsorbable hyaluronic acid and polyethylene glycol superfine composite fiber membrane material and a preparation method and application thereof. The composite fiber membrane material is prepared from 5 to 90 mass percent of hyaluronic acid and 10 to 95 mass percent of low-molecular-weight polyethylene glycol by taking water as a solvent, wherein fibers in the composite superfine fiber membrane have a spider silk structure and the fiber diameter is 100nm to 10mu m. The low-molecular-weight polyethylene glycol is adopted, so that the hyaluronic acid accounts for 5 mass percent of mixed solution of hyaluronic acid and polyethylene glycol, and the yield of the composite superfine fibers can be improved. The material has the advantages of high biocompatibility, biodegradability and bioabsorbability, light weight, softness, high air permeability and the like, and can be used as a hemostatic material, a wound dressing and a tissue engineering scaffold material.
Year: 2010
Country: CN
Doc No: 101892559