23 Jul Honeycomb polymer-based bionic porous scaffold material and preparation method thereof
Abstract
The invention discloses a honeycomb polymer-based bionic porous scaffold material and a preparation method thereof. Natural plant tissues are used as templates. The method comprises the following steps of: performing vacuum carbonation, melting, permeating in water-soluble salt, performing oxidation and carbon removal on the templates to obtain template carrying porous salt, and finally performing the processes of vacuum/pressure biological macromolecular solution soaking, vacuum drying, desalting treatment and the like to prepare the honeycomb polymer-based bionic porous scaffold material. The prepared bionic porous scaffold material has a honeycomb porous structure based on the plant tissues, the porosity is 70 to 95 percent, and the aperture is 10 to 160 microns. The preparation methodis widely applied to water-insoluble biological macromolecular materials, and is easy to realize regulation and control of physicochemical, mechanical and biological properties of porous scaffolds. The honeycomb polymer-based bionic porous scaffold material and the preparation method thereof have special significance for realizing regenerative repair of defective tissues of peripheral nerves, muscle tendons, ligaments and the like with longitudinal morphology by using tissue engineering technology, and have broad practical application prospect.
Year: 2011
Country: CN
Doc No: 102028972