23 Jul Gelatin cell scaffold with controllable porous structure and preparation method thereof
Abstract
The invention provides a gelatin cell scaffold with a controllable porous structure and a preparation method thereof. The preparation method comprises the following steps: firstly, preparing uniform latex emulsion through an emulsion process; secondly, adding a cross-linking agent into the latex emulsion to prepare gelatin microspheres; thirdly, bonding the gelatin microspheres in a crosslinking manner in a demulsification process to form gel; lastly, performing freeze drying on the gel to obtain the gelatin cell scaffold. The gelatin cell scaffold with the controllable porous structure is prepared by bonding the gelatin microspheres of different particle sizes, so that the problem that the conventional cell scaffold is non-uniform in particle size and is uncontrollable in size is solved effectively. The gelatin cell scaffold provided by the invention has high biocompatibility, biodegradability and higher mechanical performance. Moreover, the preparation method is green, is environmentally friendly, is easy to operate, and is feasible. Thus, the gelatin cell scaffold provided by the invention has a good market application prospect in the field of tissue engineering.
Year: 2018
Country: CN
Doc No: 108126239